Recovery & Repair · commonly explored around recovery and tissue repair
BPC-157
BPC-157 is a 15-amino-acid peptide based on a protein found in stomach juice. In rat studies it sped up healing of tendons, ligaments, muscle and the gut lining, making it one of the most talked-about recovery peptides.
Informational profile
No verified OnimaChain inventory for this profile.
Also known as Body Protection Compound 157 · Pentadecapeptide BPC 157 · PL 14736 · Bepecin
- Sequence
- GEPPPGKPADDAGLV
- Length
- 15 residues
- MW
- 1419.55 Da computed
- Product tags
- cytoprotective · gastric fragment · pentadecapeptide
- Checked sources
- 5 sources in our record
- Structure provenance
- Sequence-derived illustration (not a measured structure)
Video intro
BPC-157 in ten seconds.
Coming soon.
Meet BPC-157
The short version, before the deep dive.
BPC-157 is a 15-amino-acid peptide based on a protein found in stomach juice. In rat studies it sped up healing of tendons, ligaments, muscle and the gut lining, making it one of the most talked-about recovery peptides.
PulseChain
What’s new with BPC-157
Section B
The quick read
Section C
Research at a glance
A simple picture of the sources we have checked. More color means more records in that category—not that the product works better.
Filled = we have checked studies of that kind · hollow = none yet · dashed = not checked yet. This is a picture of what exists, not a score.
| # | Dimension | Verified | How |
|---|---|---|---|
| 1 | Cells in a dish (in vitro) | 1 | Checked studies done on cells in a lab dish. |
| 2 | Mice | 0 · none yet | Checked studies whose title says it was done in mice. |
| 3 | Rats | 1 | Checked studies whose title says it was done in rats. |
| 4 | Other animals | 0 · none yet | Checked studies whose title names another animal. |
| 5 | People, observed | 0 · none yet | Checked studies that watched people without a controlled trial. |
| 6 | Single-person reports | 0 · none yet | Checked reports about one patient (case reports). |
| 7 | Phase I trial | 0 · none yet | Checked early safety trials in a small group of people. |
| 8 | Phase II trial | 0 · none yet | Checked mid-size trials testing whether it works. |
| 9 | Phase III trial | 0 · none yet | Checked large trials, the kind regulators look at. |
| 10 | Approved use | Not checked yet | Not checked yet — we have not connected regulator records. |
| 11 | Repeated by others | Not checked yet | Not checked yet — we do not track repeat studies yet. |
| 12 | Separate research teams | Pang JH · Bayrak BY · Staresinic M · Cushman DM · Apostolakos JM | How many different senior authors the checked studies have. A rough stand-in for separate teams. |
| 13 | How it works | 1 | Checked studies that looked at the mechanism, based on their summary. |
| 14 | Years of research | 2011–2026 | From the oldest to the newest checked study. |
Section D
What the sources looked at
These topics come only from sources in our record. We do not add a topic just because it is popular online.
A source studied
Tendon research
Checked sources: PMID 21030672, PMID 42542926, PMID 41754849
A source studied
Ligament research
No checked source added yet
A source studied
Gastrointestinal research
No checked source added yet
A source studied
Blood-vessel signaling
No checked source added yet
People discuss
Recovery talk online
Live community feeds are not connected yet.
Section E
Why people look it up
A plain-language starting point. This is not a promise that the product will cause a result.
recovery and tissue repair
See BPC-157 beside similar names.
The Portal of Tides lets you switch between a constellation, connection view, checked-source timeline, and topic map. It uses the products already in our collection—no fake customer counts.
Section F
What the record can tell us
A product page can show what was studied. It cannot promise what will happen to a person.
What we can show
- Tendon research3 checked
- Ligament research0 checked
- Gastrointestinal research0 checked
- Blood-vessel signaling0 checked
What we cannot promise
A lab result, animal study, online story, or product page cannot tell you what will happen to you. That question needs qualified medical guidance.
Section G
Claims people make
The big claims tied to this product. Open one to see where it came from and how it spread.
Section H
How far it has been tested
From cells in a dish, to mice, rats, bigger animals, people, proper trials, and finally regulator approval. The light stops where the checked studies stop.
tendon
Tested as far as: Rat — and no further
- Cells in a disha checked study reached this stage
- Mouseno checked study has reached this stage
- Rata checked study reached this stagereached
- Bigger animalno checked study has reached this stagestops here
- Peopleno checked study has reached this stage
- Proper human trialno checked study has reached this stage
- Approved by regulatorsno checked study has reached this stage
Section I
How many separate teams
Ten papers from one lab are not ten separate confirmations.
Separate senior authors (a rough count of teams)
5 / 5 records
- Pang JH1 record(s)
- Bayrak BY1 record(s)
- Staresinic M1 record(s)
- Cushman DM1 record(s)
- Apostolakos JM1 record(s)
Universities, funding and who cites whom: not checked yet. PubMed’s summary does not include that, so it needs another data source.
Section J
What doesn’t fit?
If a study disagrees, it goes here. We do not hide it.
Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study.
Jt Dis Relat Surg · 2026 · 8 authors · senior author Bayrak BY · doi 10.52312/jdrs.2026.2951
“The BPC-157 group showed numerically lower scores without reaching statistical significance for total scores.” — from the study summary, PubMed ID 42542926
Checked against PubMed on 2026-09-22 · PubMed ↗
No study we have checked pushes back yet
Studies that found nothing, disagree, or criticize the method will show up here once we add them. A study that only partly agrees is not the same as one that disagrees.
Section K
Timeline
What happened and when. Studies in one lane, real-world reports in another.
Research
1 event
CLAIM-BPC157-TENDON-REPAIR
Claim record created
Before
— (no prior state)
After
tracked
Trials
0 events
No trial milestones are indexed to this exact record yet.
Regulatory
0 events
No regulator decisions listed yet.
Real-world reports
0 events
No real-world reports yet — social platforms are not connected.
Section L
Sources
Every study we used. Only studies we confirmed on PubMed are shown as sources. Where a drug is FDA-approved, its official label sits beside them — that is an approval, not a sales pitch.
No official FDA label for this product
We only attach an FDA record when the molecule is an approved drug and we have checked the application number. Most research peptides will stay empty here.
The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.
J Appl Physiol (1985) · 2011 · 5 authors · senior author Pang JH · doi 10.1152/japplphysiol.00945.2010
Checked against PubMed on 2026-09-22 · PubMed ↗
Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study.
Jt Dis Relat Surg · 2026 · 8 authors · senior author Bayrak BY · doi 10.52312/jdrs.2026.2951
Checked against PubMed on 2026-09-22 · PubMed ↗
Tendon, Ligament, and Muscle Injury, Osteotendinous, Myotendinous, and Muscle-to-Bone Junction Therapy Perspectives with Growth Factors and Stable Gastric Pentadecapeptide BPC 157-A Review.
Pharmaceuticals (Basel) · 2026 · 21 authors · senior author Staresinic M · doi 10.3390/ph19020309
Checked against PubMed on 2026-09-22 · PubMed ↗
Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing.
Curr Rev Musculoskelet Med · 2025 · 5 authors · senior author Cushman DM · doi 10.1007/s12178-025-09990-7
Checked against PubMed on 2026-09-22 · PubMed ↗
Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.
HSS J · 2025 · 7 authors · senior author Apostolakos JM · doi 10.1177/15563316251355551
Checked against PubMed on 2026-09-22 · PubMed ↗
The building blocks, one by one
| # | Code | Residue | Class | Chirality | Features |
|---|---|---|---|---|---|
| 1 | G | Glycine | special | L | flexible |
| 2 | E | Glutamate | negative | L | |
| 3 | P | Proline | special | L | Proline kink |
| 4 | P | Proline | special | L | Proline kink |
| 5 | P | Proline | special | L | Proline kink |
| 6 | G | Glycine | special | L | flexible |
| 7 | K | Lysine | positive | L | |
| 8 | P | Proline | special | L | Proline kink |
| 9 | A | Alanine | hydrophobic | L | |
| 10 | D | Aspartate | negative | L | |
| 11 | D | Aspartate | negative | L | |
| 12 | A | Alanine | hydrophobic | L | |
| 13 | G | Glycine | special | L | flexible |
| 14 | L | Leucine | hydrophobic | L | |
| 15 | V | Valine | hydrophobic | L |
